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Dual Phase Comprehensive Digestive Enzymes

Hypo Zymase is a gentle yet highly effective, dual phase digestive product designed specifically to provide support for the stomach and small intestine. This product presents a powerful synergistic blend of two types of HCl (betaine) and Glutamic acid, enzymes, ox bile and organic (bitter) botanicals to gently and effectively bring
balancing terrain factors to the correct binding sites.

As different enzymes require activation at different pH levels our exclusive enteric matrix formulation generates a pH sensitive release of the right synergistic ingredients at the “right time, at the right level and in the right sequence”. This insures that the correct enzymes are released in the gastric phase while the additional synergists are released in the duodenal phase. This is a significant point as many HCl digestive products tend to create dependencies due to their lack of synergistic ingredients and “over-amped” HCl content. Hypo Zymase provides the right level of HCl therapy and, typically will not cause a burning sensation or dependence like the straight forms of betaine often do. This is especially true for older patients who often require hydrochloric acid therapy.

The small intestine participates in all aspects of digestion, absorption and transport of ingested materials. It secretes a variety of digestive and protective substances as well as receiving the secretions of the pancreas, liver and gall bladder. Conditions involving the small intestine often result in malabsorption syndromes characterized by multiple nutrient deficiencies.

Common causes of malabsorption also include celiac disease (gluten intolerance), food allergy or intolerance, intestinal infections and Crohn’s.

Individuals suffering with stomach and intestinal problems most frequently assume that heartburn, indigestion, gas, and reflux are caused by overproduction of stomach acid. This is a common misconception, due to the fact that often, symptoms of stomach acid (hydrochloric acid, HCl) over-production and under production are virtually identical.

It has been theorized that well over half of the U.S. population beyond the age of fifty years is underproducing hydrochloric acid on a constant basis, leading to a host of digestive and immune disturbances. Of course, one need not be of middle age to have this problem, nowadays it’s not uncommon in younger persons as well. (Note the increase in allergies and sensitivities, obesity, learning disorders and a plethora of digestive disorders are now present in the younger population).

Achlorhydria and hypochlorhydria have also been linked to peptic ulcer disease and to Helicobacter pylori overgrowth.

Hypochlorhydria can also cause an increased bacterial colonization of the small intestine. In addition to gastric acid, other factors that limit bacterial colonization include normal bile flow and peristalsis. It has also been suggested that gastric acid acts as an anti-tumor defence, and that achlorhydria pre-disposes patients to gastric cancer.

Other causes of low gastric acid production include malnutrition and excessive use of antacids and H2 receptor antagonists. This can promote inadequate mineral uptake, due to malabsorption of iron, calcium,
zinc, etc.

1 tab contains:


  • Betaine HCL 160 mg,
  • Glutamic (L) Acid 105 mg,
  • Papain (16,000 PU/mg) 55 mg,
  • Pepsin (1:10000) 105 mg,
  • Pancreatin (8X USP) 105 mg
  • Amylase 21,000 USP
  • Protease 21,000 USP


  • Lipase 1,680 USP,
  • Bromelain (2400 GDU/g) 35 mg,
  • Bile Salts (bovine) 65 mg.
  • A unique, 75 mg proprietary blend of Fenugreek seed (Trigonella foenum-graecum), Gentian root (Gentiana verna) and Ginger root (Zingiber officinale)

Do not chew. Must be taken with meals. Do not use in ulcerative gastrointestinal conditions and when aspirin or other analgesics are being used.

Dosage: 1-2 tabs, with meals only

Traditionally may assist with:

  • Digestive issues requiring differing enzyme action than vegetable based enzymes
  • Hypochlorhydria
  • Pancreatic insufficiency
  • Gall Bladder
  • Candida
  • Gastric reflux / Heartburn
  • Flatulence
  • H. pylori
  • Constipation / Diarrhea
  • Parasites
  • Allergies / Sensitivities
  • Asthma
  • Mineral malabsorption
  • Fat soluable vitamin deficiency (A, B12, E, D, F, K)

*These statements have not been evaluated be the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.